Purpose Adult survivors of childhood cancer experience difficulties in obtaining and maintaining employment. They may also play an important role in design improvement of conventional prosthetic heart valves and the design of the next generation of prosthetic valves, such asĬareer readiness in adult survivors of childhood cancer: a report from the St.
The findings of this study may be of importance in the hemodynamic performance of bileaflet mechanical heart valves. Interestingly, the maximum shear stress and wall shear stress values in both models are in the same range when heart rate is 90 beats/min (up to ~40% growth compared to that of the native valve). Also, the maximum values of shear stress and wall shear stresses downstream of the valve are proportional to heart rate in both models. The results indicate that peak values of the velocity profile downstream of the valve increase as heart rate increases, as well as the location of the maximum velocity changes with heart rate in the St. Jude Medical valve were studied in a variety of heart rates in the opening phase and the results were carefully compared. The hemodynamics of the native valve and the St. Jude Medical bileaflet mechanical heart valve with the inner diameter of 27 mm in the aortic position. The model considered in this study was a St. In this study, the hemodynamic performance of the bileaflet mechanical heart valves in a wide range of normal and physiological heart rates, that is, 60-150 beats/min, was studied in the opening phase. The heart rates of 120 or 50 beats/min may lead to hemodynamic complications, such as plaque formation and/or thromboembolism in patients. In fact, the heart rate of ~72 beats/min does not represent the entire normal physiological conditions under which the aortic or prosthetic valves function.
To date, to the best of the authors' knowledge, in almost all of the studies performed around the hemodynamics of bileaflet mechanical heart valves, a heart rate of 70-72 beats/min has been considered. Jahandardoost, Mehdi Fradet, Guy Mohammadi, Hadi Jude Medical) in the aortic position and in the opening phase: A computational study. We conclude that the program can be a useful tool for improving knowledge of cancer concepts at the 4th-grade level.Įffect of heart rate on the hemodynamics of bileaflet mechanical heart valves' prostheses ( St. The results of this study show that 4th-grade students are able to acquire gains in knowledge related to cells, cancer, and healthy living after receiving the SJCECP intervention. Seven local schools and 481 students from the Memphis area participated in the program evaluation. During the 2010-2011 academic years, we conducted a pilot evaluation of the SJCECP curriculum, with the primary objective of evaluating the impact of the intervention on knowledge acquisition and retention among 4th-grade students participating in the program. The program aimed to teach children about cancer and healthy habits that can prevent the formation of cancers into adulthood. Jude Cancer Education for Children Program (SJCECP). Jude Children's Research Hospital began developing a school-based outreach program known as the St. Jude Cancer Education for Children Program Pilot Study: Determining the Knowledge Acquisition and Retention of 4th-Grade Students.Īyers, Katherine Villalobos, Aubrey Van Kirk Li, Zhenghong Krasin, Matthew